*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM7165250
CHEMICAL NAME           : Piperidine,
                          4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4
                          -ylidene)-1-methyl-, hydrochloride
CAS REGISTRY NUMBER     : 73391-87-4
LAST UPDATED            : 199806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H21-N-S.Cl-H
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Pizotifen hydrochloride
   * Pizotyline hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 17 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4216216
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 43 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4216216
 
                            *** END OF RECORD ***