*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TM7320000 CHEMICAL NAME : Piperidine, 2,6-dimethyl-1-nitroso- CAS REGISTRY NUMBER : 17721-95-8 BEILSTEIN REFERENCE NO. : 0114715 REFERENCE : 5-20-04-00188 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C7-H14-N2-O MOLECULAR WEIGHT : 142.23 WISWESSER LINE NOTATION : T6NTJ ANO B1 F1 COMPOUND DESCRIPTOR : Tumorigen Mutagen SYNONYMS/TRADE NAMES : * 2,6-Dimethylnitrosopiperidine * N-Nitroso-2,6-dimethylpiperidine *** HEALTH HAZARD DATA *** ** TUMORIGENIC DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2813 mg/kg/50W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Gastrointestinal - tumors REFERENCE : IJCNAW International Journal of Cancer. (International Union Against Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland) V.1- 1966- Volume(issue)/page/year: 16,318,1975 *** STATUS IN U.S. *** EPA GENETOX PROGRAM 1988, Positive: S cerevisiae-reversion EPA GENETOX PROGRAM 1988, Negative: S cerevisiae-forward mutation EPA GENETOX PROGRAM 1988, Inconclusive: Carcinogenicity-mouse/rat EPA GENETOX PROGRAM 1988, Inconclusive: D melanogaster-whole sex chrom. loss EPA GENETOX PROGRAM 1988, Inconclusive: D melanogaster-partial sex chrom. loss EPA GENETOX PROGRAM 1988, Inconclusive: D melanogaster Sex-linked lethal *** END OF RECORD ***