*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM7320000
CHEMICAL NAME           : Piperidine, 2,6-dimethyl-1-nitroso-
CAS REGISTRY NUMBER     : 17721-95-8
BEILSTEIN REFERENCE NO. : 0114715
REFERENCE               : 5-20-04-00188 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C7-H14-N2-O
MOLECULAR WEIGHT        : 142.23
WISWESSER LINE NOTATION : T6NTJ ANO B1 F1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 2,6-Dimethylnitrosopiperidine
   * N-Nitroso-2,6-dimethylpiperidine
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2813 mg/kg/50W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Sense Organs and Special Senses (Olfaction) - tumors
   Gastrointestinal - tumors
REFERENCE :
   IJCNAW International Journal of Cancer.  (International Union Against
   Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland)  V.1-    1966-
   Volume(issue)/page/year: 16,318,1975

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: S cerevisiae-reversion
   
   EPA GENETOX PROGRAM 1988, Negative: S cerevisiae-forward mutation
   
   EPA GENETOX PROGRAM 1988, Inconclusive: Carcinogenicity-mouse/rat
   
   EPA GENETOX PROGRAM 1988, Inconclusive: D melanogaster-whole sex chrom. loss
   
   EPA GENETOX PROGRAM 1988, Inconclusive: D melanogaster-partial sex chrom.
   loss
   
   EPA GENETOX PROGRAM 1988, Inconclusive: D melanogaster Sex-linked lethal

 
                            *** END OF RECORD ***