*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM7340074
CHEMICAL NAME           : 3,4-Piperidinediol,
                          1,3-dimethyl-4-ethynyl-6-(4-fluorophenyl)-,
                          (3-alpha,4-alpha,6-beta)-
CAS REGISTRY NUMBER     : 121368-78-3
LAST UPDATED            : 199112
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H18-F-N-O2
MOLECULAR WEIGHT        : 263.34
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (3-alpha,4-alpha,6-beta)-1,3-Dimethyl-4-ethynyl-6-(4-fluorophenyl)-3,4-p
     iperidinediol
   * 3a,4a-Dihydroxy-1e,3e-dimethyl-6e-(4-fluorophenyl)-4e-ethynylpiperidine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 131 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   KHFZAN Khimiko-Farmatsevticheskii Zhurnal.  Chemical Pharmaceutical Journal.
    For English translation, see PCJOAU.  (V/O Mezhdunarodnaya Kniga, 113095
   Moscow, USSR)  V.1-    1967-  Volume(issue)/page/year: 23,178,1989
 
                            *** END OF RECORD ***