*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM7510000
CHEMICAL NAME           : 2,6-Piperidinedione,
                          4-(2-hydroxy-5,7-dimethyl-4-oxo-6,8-decadiennyl)-
CAS REGISTRY NUMBER     : 51867-94-8
BEILSTEIN REFERENCE NO. : 1545072
REFERENCE               : 5-21-13-00443 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H25-N-O4
MOLECULAR WEIGHT        : 307.43
WISWESSER LINE NOTATION : T6VMVTJ E1YQ1VY1&1UY1&1U2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Antibiotic TS 885
   * 3-(5,7-Dimethyl-4-oxo-2-hydroxy-6,8-decadienyl)glutarimide
   * 9-Methylstreptimidone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 280 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 27,206,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 27,206,1974
 
                            *** END OF RECORD ***