*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM7527800
CHEMICAL NAME           : 2,6-Piperidinedione,
                          1,1'-(1,4-piperazinediylbis(methylene))bis(3-ethyl-3-
                          phenyl-
CAS REGISTRY NUMBER     : 57403-12-0
BEILSTEIN REFERENCE NO. : 0773155
REFERENCE               : 5-23-01-00041 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C32-H40-N4-O4
MOLECULAR WEIGHT        : 544.76
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1,1'-(1,4-Piperazinediylbis(methylene))bis(3-ethyl-3-phenyl-2,6-piperidi
     nedione)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 32,243,1975
 
                            *** END OF RECORD ***