*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : TM7640000
CHEMICAL NAME : Piperidine, 2-(2,2-diphenyl-1,3-dioxolan-4-yl)-,
hydrochloride, l-
CAS REGISTRY NUMBER : 23257-58-1
LAST UPDATED : 199012
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C20-H23-N-O2.Cl-H
MOLECULAR WEIGHT : 345.90
WISWESSER LINE NOTATION : T6MTJ B- DT5O COTJ BR& BR &GH -L
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* CL 912C
* l-Dioxadrol hydrochloride
* l-2-(2,2-Diphenyl-1,3-dioxolan-4-yl)piperidine hydrochloride
* l-2,2-Diphenyl-4-(2-piperidyl)-1,3-dioxolane hydrochloride
* Levoxadrol hydrochloride
* Levoxan
* U-22,304A
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 310 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 153,105,1965
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 230 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
Behavioral - ataxia
Lungs, Thorax, or Respiration - other changes
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 153,105,1965
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 25 mg/kg
TOXIC EFFECTS :
Behavioral - anticonvulsant
Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 153,105,1965
*** END OF RECORD ***