*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TM7860500 CHEMICAL NAME : Piperidine, 4,4-diphenyl-1-tert-pentyl-, hydrochloride LAST UPDATED : 199112 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C22-H29-N.Cl-H MOLECULAR WEIGHT : 343.98 WISWESSER LINE NOTATION : T6NTJ A1X1&1&1 DR& DR &GH COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 4,4-Diphenyl-1-tert-pentylpiperidine hydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >800 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - irritability Skin and Appendages - hair REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 34,233,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 90 mg/kg TOXIC EFFECTS : Behavioral - excitement Behavioral - changes in motor activity (specific assay) REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 34,233,1984 *** END OF RECORD ***