*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM6408250
CHEMICAL NAME           : 4-Piperidinecarboxylic acid,
                          4-phenyl-1-(3-(phenylamino)propyl)-, ethyl ester
CAS REGISTRY NUMBER     : 13495-09-5
BEILSTEIN REFERENCE NO. : 0334632
REFERENCE               : 5-22-02-00490 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H30-N2-O2
MOLECULAR WEIGHT        : 366.55
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Alvodine
   * Anopridine
   * Cimadon
   * Isonipecotic acid, 1-(3-anilinopropyl)-4-phenyl-, ethyl ester
   * NIH 7590
   * 4-Phenyl-1-(3-(phenylamino)propyl)-4-piperidinecarboxylic acid ethyl  
   ester
   * Pimadin
   * Pimadin (analgesic)
   * Pimadine
   * Piminodine
   * WIN 14098
   * WIN 14098-2
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 228 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   3,358,1961
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 39 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   3,358,1961
 
                            *** END OF RECORD ***