*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TM6408250 CHEMICAL NAME : 4-Piperidinecarboxylic acid, 4-phenyl-1-(3-(phenylamino)propyl)-, ethyl ester CAS REGISTRY NUMBER : 13495-09-5 BEILSTEIN REFERENCE NO. : 0334632 REFERENCE : 5-22-02-00490 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C23-H30-N2-O2 MOLECULAR WEIGHT : 366.55 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Alvodine * Anopridine * Cimadon * Isonipecotic acid, 1-(3-anilinopropyl)-4-phenyl-, ethyl ester * NIH 7590 * 4-Phenyl-1-(3-(phenylamino)propyl)-4-piperidinecarboxylic acid ethyl ester * Pimadin * Pimadin (analgesic) * Pimadine * Piminodine * WIN 14098 * WIN 14098-2 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 228 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,358,1961 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 39 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Gastrointestinal - changes in structure or function of salivary glands REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,358,1961 *** END OF RECORD ***