*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM9314000
CHEMICAL NAME           : 2-Piperidineethanol, 1-methyl-alpha-phenyl-,
                          (R*,R*)-(+-)-
CAS REGISTRY NUMBER     : 1630-44-0
LAST UPDATED            : 199303
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H21-N-O
MOLECULAR WEIGHT        : 219.36
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (R*,R*)-(+-)-1-Methyl-alpha-phenyl-2-piperidineethanol
   * (+-)-Sedamine
   * dl-Sedamine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 61 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,835,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 69800 ug/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,835,1961
 
                            *** END OF RECORD ***