*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TN1296000
CHEMICAL NAME           : Piperidine, 2-methyl-N-nitroso-, R(-)-
CAS REGISTRY NUMBER     : 14026-03-0
LAST UPDATED            : 199304
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C6-H12-N2-O
MOLECULAR WEIGHT        : 128.20
WISWESSER LINE NOTATION : T6NTJ ANO B1 -R,-
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * R(-)-N-Nitroso-2-methyl-piperidin
   * R(-)-N-Nitroso-2-methylpiperidine
   * R(-)-N-Nitroso-alpha-pipecoline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Liver - other changes
REFERENCE :
   ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie.  (Berlin,
   Fed. Rep. Ger.)  V.76-92, 1971-78.  For publisher information, see JCROD7.
   Volume(issue)/page/year: 79,118,1973
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6300 mg/kg/40W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Brain and Coverings - tumors
REFERENCE :
   ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie.  (Berlin,
   Fed. Rep. Ger.)  V.76-92, 1971-78.  For publisher information, see JCROD7.
   Volume(issue)/page/year: 79,118,1973

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: Carcinogenicity-mouse/rat

 
                            *** END OF RECORD ***