The following tests are designed to provide assurance that oral liquids will, when transferred from the original container, deliver the volume of dosage form that is declared on the label of the article. These tests are applicable to products labeled to contain not more than 250 mL, whether supplied as liquid preparations or liquid preparations that are constituted from solids upon the addition of a designated volume of a specific diluent. They are not required for an article packaged in single-unit containers when the monograph includes the Uniformity of Dosage Units 905 test.

For the determination of deliverable volume, select not fewer than 30 containers, and proceed as follows for the dosage form designated.

Being careful to avoid the formation of air bubbles, gently pour the contents of each container into separate dry graduated cylinders of a rated capacity not exceeding two and a half times the volume to be measured, and calibrated “to contain”. Allow each container to drain for a period not to exceed 30 minutes, for multiple-unit containers and 5 seconds for single-unit containers, unless otherwise specified in the monograph. When free from air bubbles, measure the volume of each mixture. Alternatively, in the case of products of low volume packaged in single-unit containers, the volume can be computed as follows: (1) discharge the container contents into a suitable tared container (allowing drainage for not more than 5 seconds); (2) determine the weight of the contents; and (3) compute the volume after determining the density.

Use the following criteria to determine compliance with this test.