Title: 2-Amino-2-methyl-1-propanol
CAS Registry Number: 124-68-5
Additional Names: 2,2-Diethylethanolamine; 2-hydroxymethyl-2-propylamine; AMP
Molecular Formula: C4H11NO
Molecular Weight: 89.14
Percent Composition: C 53.90%, H 12.44%, N 15.71%, O 17.95%
Literature References: An amino alcohol prepd by reduction of the corresp nitro compound: H. B. Hass, B. M. Vanderbilt, US 2139122 (1938 to Purdue Res. Found.); Johnson, Degering, J. Org. Chem. 8, 7 (1943). Toxicological evaluation and review: Cosmetic, Toiletry and Fragrance Assoc. (CTFA), J. Am. Coll. Toxicol. 9, 203-228 (1990).
Properties: Crystalline mass, mp 30-31°. (The commercial product may be a viscous liquid.) d2020 0.934. nD20 1.449. bp760 165°; bp10 67.4°. Miscible with water. Sol in alcohols. pH of 0.1M aq soln 11.3. LD50 in mice, rats (g/kg): 2.15 ± 0.2, 2.90 ± 0.14 orally (CTFA).
Melting point: mp 30-31°
Boiling point: bp760 165°; bp10 67.4°
Index of refraction: nD20 1.449
Density: d2020 0.934
Toxicity data: LD50 in mice, rats (g/kg): 2.15 ± 0.2, 2.90 ± 0.14 orally (CTFA)
Use: In the synthesis of surface-active agents, vulcanization accelerators, pharmaceuticals. As emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, leather dressings, textile specialties, polishes, cleaning compounds, so-called soluble oils. In hair sprays, wave sets and hair dyes. Absorbent for acidic gases. For use as a drug see Pamabrom. |