Title: 5-Methylpyrazole-3-carboxylic Acid
CAS Registry Number: 402-61-9
Molecular Formula: C5H6N2O2
Molecular Weight: 126.11
Percent Composition: C 47.62%, H 4.80%, N 22.21%, O 25.37%
Literature References: Prepn: Knorr, MacDonald, Ann. 279, 219 (1894); Lehninger, J. Am. Chem. Soc. 64, 2507 (1942). Hypoglycemic metabolite of 3,5-dimethylpyrazole: Smith et al., J. Med. Chem. 8, 350 (1965).
Properties: Crystals from water, mp 236-237°.
Melting point: mp 236-237°
Derivative Type: Methyl ester
Molecular Formula: C6H8N2O2
Molecular Weight: 140.14
Percent Composition: C 51.42%, H 5.75%, N 19.99%, O 22.83%
Properties: Crystals, mp 75-78°.
Melting point: mp 75-78°
Derivative Type: Ethyl ester
Molecular Formula: C7H10N2O2
Molecular Weight: 154.17
Percent Composition: C 54.53%, H 6.54%, N 18.17%, O 20.76%
Properties: Crystals, mp 83°.
Melting point: mp 83°
CAUTION: A powerful hypoglycemic agent in rats (characteristic of pyrazoles). |