Title: 5¢-Uridylic Acid
CAS Registry Number: 58-97-9
Additional Names: Uridine 5¢-phosphoric acid; uridine 5¢-monophosphate; UMP
Molecular Formula: C9H13N2O9P
Molecular Weight: 324.18
Percent Composition: C 33.34%, H 4.04%, N 8.64%, O 44.42%, P 9.55%
Literature References: Nucleotide; widely distributed in nature. Synthesis by phosphorylation of 2¢,3¢-O-benzylidene uridine with diphenyl phosphorochloridate: Brown et al., J. Chem. Soc. 1950, 408; Smith, Biochem. Prep. 8, 130 (1961). Monograph on the synthesis of nucleotides: G. R. Pettit, Synthetic Nucleotides vol. 1 (Van Nostrand Reinhold, New York, 1972) 252 pp. Crystal structure of hydrated barium salt: Shefter, Trueblood, Acta Crystallogr. 18, 1067 (1965). Reviews: see Uridine.
Properties: Free acid: pKa1¢ 6.4, pKa2¢ 9.5. uv max (pH 7.0): 262 nm (aM 10,000).
pKa: pKa1¢ 6.4, pKa2¢ 9.5
Absorption maximum: uv max (pH 7.0): 262 nm (aM 10,000)
Derivative Type: Disodium salt dihydrate
Molecular Formula: C9H11N2Na2O9P.2H2O
Molecular Weight: 404.18
Percent Composition: C 26.74%, H 3.74%, N 6.93%, Na 11.38%, O 43.54%, P 7.66%
Properties: White powder, characteristic meaty taste. uv max (0.1M HCl): 262 nm (e 10,000). Soly in water at 20°: about 41 g/100 ml H2O.
Absorption maximum: uv max (0.1M HCl): 262 nm (e 10,000)
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