Title: Amcinonide
CAS Registry Number: 51022-69-6
CAS Name: (11b,16a)-21-(Acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxypregna-1,4-diene-3,20-dione
Additional Names: 9-fluoro-11b,16a,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclopentanone 21-acetate
Manufacturers' Codes: CL-34699
Trademarks: Amciderm (Hermal); Cyclocort (Fujisawa); Penticort (Lederle)
Molecular Formula: C28H35FO7
Molecular Weight: 502.57
Percent Composition: C 66.92%, H 7.02%, F 3.78%, O 22.28%
Literature References: Prepn: W. Shultz et al., DE 2437847 (1975 to Am. Cyanamid), C.A. 83, 10608g (1975). Bioavailability study: R. Woodford, J. M. Haigh, Curr. Ther. Res. 26, 301 (1979). Therapeutic use in eczematoid conditions: G. L. Rocha et al., ibid. 19, 538 (1976); E. W. Rosenberg, Cutis 24, 642 (1979).
Therap-Cat: Glucocorticoid.
Keywords: Glucocorticoid. |