Title: Bradycor
CAS Registry Number: 140661-97-8
Manufacturers' Codes: CP-0127
Molecular Formula: C128H194N40O28S2
Molecular Weight: 2805.29
Percent Composition: C 54.80%, H 6.97%, N 19.97%, O 15.97%, S 2.29%
Literature References: Bradykinin antagonist. Dimer of D-Arg0-[Hyp3, Cys6, D-Phe7, Leu8]-bradykinin joined by a bissuccinimidohexane linker via the sulfhydryl moieties of the cysteine residues. Prepn: J. C. Cheronis et al., WO 9217201 (1992 to Cortech); eidem, J. Med. Chem. 35, 1563 (1992). Effect on survival in endotoxin shock in animals: E. T. Whalley et al., Agents Actions Suppl. 38 (3), 413 (1992).
Therap-Cat: In treatment of systemic inflammatory response syndrome.
Keywords: Bradykinin Antagonist. |