Title: Chloraminophenamide
CAS Registry Number: 121-30-2
CAS Name: 4-Amino-6-chloro-1,3-benzenedisulfonamide
Additional Names: 4-amino-6-chloro-m-benzenedisulfonamide; 5-chloro-2,4-bis(sulfonamido)aniline; 6-amino-4-chlorobenzene-1,3-disulfonamide; 5-chloro-2,4-disulfamylaniline
Trademarks: Idorese
Molecular Formula: C6H8ClN3O4S2
Molecular Weight: 285.73
Percent Composition: C 25.22%, H 2.82%, Cl 12.41%, N 14.71%, O 22.40%, S 22.44%
Literature References: Prepn: Novello, Sprague, J. Am. Chem. Soc. 79, 2028 (1957); Novello, US 2809194; US 2965655; US 2965656 (1957, 1960, 1960 all to Merck & Co.); Novello et al., J. Org. Chem. 25, 965 (1960).
Properties: Crystals from aq ethanol, mp 251-252°. uv max (ethanol): 223.5-224.5, 265-266, 312-314 nm (e 41776, 18633, 3874). Slightly sol in water; more freely sol in alkalies.
Melting point: mp 251-252°
Absorption maximum: uv max (ethanol): 223.5-224.5, 265-266, 312-314 nm (e 41776, 18633, 3874)
Therap-Cat: Diuretic.
Keywords: Diuretic; Sulfonamide Derivatives. |