Title: Ethionine
CAS Registry Number: 13073-35-3
CAS Name: S-Ethyl-L-homocysteine
Additional Names: 2-amino-4-(ethylthio)butyric acid; a-amino-g-(ethylmercapto)butyric acid; homocysteine S-ethyl ether
Molecular Formula: C6H13NO2S
Molecular Weight: 163.24
Percent Composition: C 44.15%, H 8.03%, N 8.58%, O 19.60%, S 19.64%
Line Formula: CH3CH2SCH2CH2CH(NH2)COOH
Literature References: Prepn from ethanethiol and acrolein, purification via Zn salt: Norton, US 2840587 (1958 to Dow). Prepn of DL-form and L-form: Armstrong, Lewis, J. Org. Chem. 16, 749 (1951). Resolution of D- and L-isomers: Greenstein et al., J. Biol. Chem. 204, 307 (1953). Review: E. Farber, "Ethionine Carcinogenesis" in A. Haddow, S. Weinhouse, Advan. Cancer Res. vol. 7 (Academic Press, New York, 1963) pp 383-474.
Properties: Crystals, dec 272-274°. [a]D24 +25.1°. Also reported as [a]D23 +20.1° (1N HCl) (Armstrong, Lewis).
Optical Rotation: [a]D24 +25.1°; [a]D23 +20.1° (1N HCl) (Armstrong, Lewis)
Derivative Type: DL-Form
CAS Registry Number: 67-21-0
Properties: Crystals, dec 257-260°. Also reported as dec 272-284° (Armstrong, Lewis).
|