Title: Mebiquine
CAS Registry Number: 23910-07-8
CAS Name: 8-[(Dihydroxybismutho)oxy]-6-methylquinoline
Additional Names: dihydroxy(6-methyl-8-quinolinolato)bismuth; 6-methyl-8-bismuthohydroxyquinoline; DV1
Trademarks: Diarétyl
Molecular Formula: C10H10BiNO3
Molecular Weight: 401.17
Percent Composition: C 29.94%, H 2.51%, Bi 52.09%, N 3.49%, O 11.96%
Literature References: Prepn by the addition of 6-methyl-8-hydroxyquinoline to a solution of bismuth nitrate: Riviere et al., DE 1811581; eidem, US 3591591 (1969, 1971 to Ugine Kuhlmann). Parasiticidal properties: R. Cavier et al., Ann. Pharm. Fr. 31, 273 (1973).
Properties: Yellow powder, insol in water, alc, weak alkaline solns. Sol in strong acids. LD50 orally in mice: >10,000 mg/kg (Cavier).
Toxicity data: LD50 orally in mice: >10,000 mg/kg (Cavier)
Therap-Cat: Antidiarrheal.
Keywords: Antidiarrheal.
Status: This monograph has been retired and is no longer subject to revision or update. |