Title: Methylguanidine
CAS Registry Number: 471-29-4
Molecular Formula: C2H7N3
Molecular Weight: 73.10
Percent Composition: C 32.86%, H 9.65%, N 57.48%
Literature References: Isoln by Brieger in 1888 from decomposing horsemeat; described as a product of putrefaction: I. Greenwald, J. Am. Chem. Soc. 41, 1109 (1919). Prepn: E. Erlenmeyer, Ber. 3, 896 (1870); E. A. Werner, J. Bell, J. Chem. Soc. 121, 1790 (1922); R. Phillips, H. T. Clarke, J. Am. Chem. Soc. 45, 1755 (1923); E. Philippi, K. Morsch, Ber. 60, 2120 (1927); T. L. Davis, E. N. Rosenquist, J. Am. Chem. Soc. 59, 2112 (1937). Toxicity data: Alles, J. Pharmacol. Exp. Ther. 28, 251 (1926); Fühner, Arch. Exp. Pathol. Pharmakol. 166, 437 (1932).
Properties: Colorless, deliquesc, strongly alkaline mass. Very sol in water; sol in alcohol. Reduces permanganate. MLD in rats (mg/kg): 250 s.c. (Alles). LD in frogs, mice (mg/kg): 170-190, 550-600 s.c. (Fühner).
Toxicity data: MLD in rats (mg/kg): 250 s.c. (Alles); LD in frogs, mice (mg/kg): 170-190, 550-600 s.c. (Fühner) |