Title: Pentolinium Tartrate
CAS Registry Number: 52-62-0
CAS Name: 1,1¢-(1,5-Pentanediyl)bis[1-methylpyrrolidinium] salt with (2R,3R)-2,3-dihydroxybutanedioic acid (1:2)
Additional Names: pentamethylene-1,5-bis(1-methylpyrrolidinium) hydrogen tartrate; pentapyrrolidinium bitartrate; pentolonium bitartrate
Manufacturers' Codes: M & B 2050A
Trademarks: Ansolysen Tartrate (Wyeth); Ansolysen Bitartrate (Wyeth); Pentilium
Molecular Formula: C23H42N2O12
Molecular Weight: 538.59
Percent Composition: C 51.29%, H 7.86%, N 5.20%, O 35.65%
Literature References: General procedure of prepn: Libman et al., J. Chem. Soc. 1952, 2305. Ganglionic blocking agent.
Properties: Crystals, dec 203°. Non-hygroscopic. Acid taste. Freely sol in water or in 25% aq polyvinylpyrrolidone soln. One gram dissolves in 0.4 ml water, in 810 ml ethanol. Insol in ether, chloroform. A 10% aq soln has a pH of about 3.5.
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive; Quaternary Ammonium Compounds. |