Title: Plasmocid
CAS Registry Number: 551-01-9
CAS Name: N,N-Diethyl-N¢-(6-methoxy-8-quinolinyl)-1,3-propanediamine
Additional Names: 8-(3-diethylaminopropylamino)-6-methoxyquinoline; 6-methoxy-8-(3-diethylaminopropylamino)quinoline
Manufacturers' Codes: 710-F; SN-3115; Fourneau 710
Trademarks: Antimalarine; Rhodoquine
Molecular Formula: C17H25N3O
Molecular Weight: 287.40
Percent Composition: C 71.04%, H 8.77%, N 14.62%, O 5.57%
Literature References: Prepn: Fourneau et al., Ann. Inst. Pasteur 44, 503 (1930); 46, 514 (1931); 50, 731 (1933); Magidson, Strukov, Arch. Pharm. 271, 359 (1933); Strukov, SU 39105 (1934), C.A. 30, 3445 (1936); Magidson et al., J. Appl. Chem. USSR 9, 304 (1936); Giral, Ciencia (Mexico City) 6, 253 (1945), C.A. 40, 3563 (1946); Yanko et al., J. Am. Chem. Soc. 67, 664 (1945).
Properties: Oily liquid, d424 1.0569. bp1.0 182°. nD24 1.5855.
Boiling point: bp1.0 182°
Index of refraction: nD24 1.5855
Density: d424 1.0569
Derivative Type: Dihydrochloride
Molecular Formula: C17H27Cl2N3O
Molecular Weight: 360.32
Percent Composition: C 56.67%, H 7.55%, Cl 19.68%, N 11.66%, O 4.44%
Properties: Yellow crystals, mp 218-220°. Slightly sol in water, alcohol.
Melting point: mp 218-220°
Derivative Type: Diphosphate
Properties: Yellow crystals, mp 169-171°. Slightly sol in water, alcohol.
Melting point: mp 169-171°
NOTE: The name Rhodoquine was first applied to 8-(3-dimethylaminopropylamino)-6-methoxyquinoline.
Therap-Cat: Antimalarial.
Keywords: Antimalarial. |