Title: Proheptazine
CAS Registry Number: 77-14-5
CAS Name: Hexahydro-1,3-dimethyl-4-phenyl-1H-azepin-4-ol propanoate (ester)
Additional Names: DL-a-1,3-dimethyl-4-phenyl-4-propionoxyazacycloheptane; 1,3-dimethyl-4-phenyl-4-propionoxyhexamethylenimine; 4-phenyl-4-propionoxy-1,3-dimethylazacycloheptane; 4-propionoxy-1,3-dimethyl-4-phenylhexamethylenimine; dimepheprimine
Manufacturers' Codes: Wy-757
Molecular Formula: C17H25NO2
Molecular Weight: 275.39
Percent Composition: C 74.14%, H 9.15%, N 5.09%, O 11.62%
Literature References: Prepn: Diamond, Bruce, US 2775589 (1956 to American Home Prod.). Structure and synthesis: Diamond et al., J. Med. Chem. 7, 57 (1964).
Properties: Liquid, bp0.3 126°. nD28 1.5182. nD21 1.5215.
Boiling point: bp0.3 126°
Index of refraction: nD28 1.5182; nD21 1.5215
Derivative Type: Hydrobromide
Molecular Formula: C17H26BrNO2
Molecular Weight: 356.30
Percent Composition: C 57.31%, H 7.36%, Br 22.43%, N 3.93%, O 8.98%
Properties: Crystals from acetone + methanol, dec 207-207.5°. Soly in water at 25°: 1-2%.
Derivative Type: Hydrochloride
Molecular Formula: C17H26ClNO2
Molecular Weight: 311.85
Percent Composition: C 65.47%, H 8.40%, Cl 11.37%, N 4.49%, O 10.26%
Properties: Crystals, dec 207°.
NOTE: This is a controlled substance (opiate): 21 CFR, 1308.11.
Therap-Cat: Analgesic (narcotic).
Keywords: Analgesic (Narcotic). |