Title: Iophenoxic Acid
CAS Registry Number: 96-84-4
CAS Name: a-Ethyl-3-hydroxy-2,4,6-triiodobenzenepropanoic acid
Additional Names: a-ethyl-3-hydroxy-2,4,6-triiodohydrocinnamic acid; a-(2,4,6-triiodo-3-hydroxybenzyl)butyric acid; a-ethyl-b-(3-hydroxy-2,4,6-triiodophenyl)propionic acid; a-ethyl-b-(2,4,6-triiodo-3-hydroxyphenyl)propionic acid; triiodoethionic acid
Trademarks: Teridax (Schering)
Molecular Formula: C11H11I3O3
Molecular Weight: 571.92
Percent Composition: C 23.10%, H 1.94%, I 66.57%, O 8.39%
Literature References: Prepn: Papa et al., J. Am. Chem. Soc. 75, 1107 (1953); GB 726987 (1955 to Sterling Drug). Toxicity data: J. O. Hoppe et al., J. Med. Chem. 13, 997 (1970).
Properties: Crystals from benzene + petr ether, mp 143-144°. LD50 i.v. in mice: 374 mg/kg (Hoppe).
Melting point: mp 143-144°
Toxicity data: LD50 i.v. in mice: 374 mg/kg (Hoppe)
Therap-Cat: Diagnostic aid (radiopaque medium¾cholecystographic).
Keywords: Diagnostic Aid (Radiopaque Medium). |