Title: Kebuzone
CAS Registry Number: 853-34-9
CAS Name: 4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedione
Additional Names: 1,2-diphenyl-4-(g-ketobutyl)-3,5-pyrazolidinedione; 1,2-diphenyl-4-(3¢-oxobutyl)-3,5-dioxopyrazolidine; ketophenylbutazone; KPB
Trademarks: Chebutan; Chepirol; Chetazolidin (Zeria); Chetil; Copirene; Ketason; Ketazone (Beytout); Pecnon (Sanken); Phloguron (Steiner); Recheton
Molecular Formula: C19H18N2O3
Molecular Weight: 322.36
Percent Composition: C 70.79%, H 5.63%, N 8.69%, O 14.89%
Literature References: Prepn: Deuss et al., US 2910481 (1959 to Geigy). Review of pharmacology: Horakova et al., Pharmacotherapeutica 1950-1959, 335-350 (1963), C.A. 60, 6072g (1964). Metabolism: Nemecek et al., Arzneim.-Forsch. 16, 1339 (1966); Queisnerova, Nemecek, Cesk. Farm. 20, 55 (1971), C.A. 75, 47077u (1971).
Properties: Crystals, mp 115.5-116.5° or 127.5-128.5° depending on cryst form.
Melting point: mp 115.5-116.5° or 127.5-128.5° depending on cryst form
Therap-Cat: Antirheumatic.
Keywords: Antiarthritic/Antirheumatic. |