Title: Kurcholessine
CAS Registry Number: 6869-47-2
CAS Name: (3b,4a,5a,7b)-3-(Dimethylamino)-4-methyl-5-conanine-5,7-diol
Molecular Formula: C25H44N2O2
Molecular Weight: 404.63
Percent Composition: C 74.21%, H 10.96%, N 6.92%, O 7.91%
Literature References: A steroidal alkaloid from Kurchi bark. Isoln from Holarrhena antidysenterica Wall., Apocynaceae: Tschesche, Otto, Ber. 95, 1144 (1962). Structure: Tschesche et al., Tetrahedron Lett. 1964, 1659.
Properties: Slender needles from ethanol; microcryst powder from acetone. mp 218.5-221.5°. [a]D20 -4 ±2° (CHCl3), +5 ±2° (c = 0.01, abs ethanol). Very sol in chloroform, methanol, ethanol, pyridine; slightly sol in warm acetone. Practically insol in ethyl acetate, benzene, petr ether, ether, water.
Melting point: mp 218.5-221.5°
Optical Rotation: [a]D20 -4 ±2° (CHCl3), +5 ±2° (c = 0.01, abs ethanol)
Status: This monograph has been retired and is no longer subject to revision or update. |