Title: Nifenalol
CAS Registry Number: 7413-36-7
CAS Name: a-[[(1-Methylethyl)amino]methyl]-4-nitrobenzenemethanol
Additional Names: a-[(isopropylamino)methyl]-p-nitrobenzyl alcohol; 1-(4-nitrophenyl)-2-(isopropylamino)ethanol; isophenethanol; INPEA
Molecular Formula: C11H16N2O3
Molecular Weight: 224.26
Percent Composition: C 58.91%, H 7.19%, N 12.49%, O 21.40%
Literature References: b-Adrenergic blocker. Prepn: Teotino et al., Farmaco Ed. Sci. 17, 252 (1962); eidem, GB 950682 (1964 to Selvi), C.A. 60, 13184h (1964). Pharmacology: Somani, Lum, J. Pharmacol. Exp. Ther. 147, 194 (1965); Almirante et al., Farmaco Ed. Sci. 21, 637 (1966). Prepn of the optical isomers: Almirante, Murmann, J. Med. Chem. 9, 650 (1966); eidem, BE 673273 (1966 to Selvi), C.A. 66, 65278d (1967).
Properties: mp 98°.
Melting point: mp 98°
Derivative Type: Hydrochloride
CAS Registry Number: 5704-60-9
Trademarks: Inpea (Selvi)
Molecular Formula: C11H16N2O3.HCl
Molecular Weight: 260.72
Percent Composition: C 50.67%, H 6.57%, N 10.74%, O 18.41%, Cl 13.60%
Properties: mp 181°.
Melting point: mp 181°
Therap-Cat: Antianginal; antiarrhythmic.
Keywords: ?Adrenergic Blocker; Antianginal; Antiarrhythmic. |