Title: Trimeprazine
CAS Registry Number: 84-96-8
CAS Name: N,N,b-Trimethyl-10H-phenothiazine-10-propanamine
Additional Names: 10-[3-(dimethylamino)-2-methylpropyl]phenothiazine; 10-(2-methyl-3-dimethylaminopropyl)phenothiazine; alimemazine; methylpromazine
Manufacturers' Codes: Bayer 1219; RP-6549
Molecular Formula: C18H22N2S
Molecular Weight: 298.45
Percent Composition: C 72.44%, H 7.43%, N 9.39%, S 10.74%
Literature References: Prepn: Jacob, Robert, US 2837518 (1958 to Rhône-Poulenc). Metabolism studies: Robinson, J. Pharm. Pharmacol. 18, 19 (1966).
Properties: Crystals, mp 68°. bp0.3 150-175°.
Melting point: mp 68°
Boiling point: bp0.3 150-175°
Derivative Type: Tartrate
CAS Registry Number: 4330-99-8
Trademarks: Panectyl (RPR); Repeltin (Fabre-Medikosma); Temaril (Allergan); Theralene (Rh>e-Poulenc); Vallergan (M & B)
Molecular Formula: (C18H22N2S)2.C4H6O6
Molecular Weight: 746.98
Percent Composition: C 64.32%, H 6.75%, N 7.50%, S 8.59%, O 12.85%
Properties: Crystals. Sol in water; slightly sol in alcohol.
Therap-Cat: Antipruritic.
Therap-Cat-Vet: Antipruritic.
Keywords: Antipruritic. |