美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Valsartan	Tablet			Refer to USP			2016/07/28
Vancomycin hydrochloride	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Vandetanib	Tablet	II (Paddle)	50	pH 1.2 Buffer [0.05 M KCl in water, adjust the pH with HCl or NaOH]	1000	5, 10, 15, 20 and 30	2015/06/25
Vardenafil HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Vardenafil HCl	Tablet (Orally Disintegrating)	II (Paddle)	50	0.1 N HCl	900	5, 10, 15 and 30	2014/05/15
Varenicline Tartrate	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Vemurafenib	Tablet	II (Paddle)	75	1% hexadecyltrimethylammonium bromide (HTAB) in 0.05 M Phosphate Buffer, pH 6.8	900	10, 15, 20, 30 and 45	2015/05/28
Venetoclax	Tablet	III (Reciprocating Cylinder) [Bottom Screen: 200 mesh stainless steel]	20 dpm	Phosphate Buffer, pH 6.8 with 0.4% sodium dodecyl sulfate (SDS) [3 small drops of antifoaming agent may be used]	250	0.25, 0.5, 0.75, 1, 1.5, 2, 3, 3.5 and 4 hours	2016/07/28
Venlafaxine Besylate	Tablet (Extended Release)	II (Paddle with sinker)	50	0.1 M NaCl in water (Degassed)	900	1, 2, 4, 6, 8, 12, 14 and 16 hours	2023/02/09
Venlafaxine HCl	Tablet (Extended Release)			Develop a dissolution method			2023/09/15
Venlafaxine HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Venlafaxine HCl	Capsule (Extended Release)			Develop a dissolution method			2023/09/15
Verapamil HCl	Tablet			Refer to USP			2008/11/04
Verapamil HCl	Capsule (Extended Release)			Refer to USP			2015/08/27
Verapamil HCl	Tablet (Extended Release)			Refer to USP			2010/06/24
Vericiguat	Tablet	II (Paddle)	75	0.01 N HCl, pH 2.0	900	5, 10, 15, 20 and 30	2022/07/07
Verteporfin	Injectable			Develop a method to characterize in vitro release.			2014/08/14
Vibegron	Tablet			Refer to FDA's Dissolution Guidance, 2018			2023/02/09
Vigabatrin	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Vilazodone HCl	Tablet	II (Paddle)	60	0.1% v/v Glacial acetic acid solution (pH 3.1)	1000	10, 15, 20, 30 and 45	2014/08/14