美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Alprazolam	Tablet (Orally Disintegrating)	II (Paddle)	50	70 mM Potassium Phosphate Buffer, pH 6.0	500	2, 5, 10, 15 and 20	2008/10/06
Alprazolam	Tablet (Extended Release)	I (Basket)	100	1% Phosphate Buffer, pH 6.0	500	1, 4, 8, 12 and 16 hours	2007/02/08
Altretamine	Capsule			Refer to USP			2010/01/29
Aluminum Hydroxide/Magnesium Trisilicate	Tablet (Chewable)			Develop a dissolution method			2022/05/12
Alvimopan	Capsule	II (Paddle	50	0.1 N HCl	900	5, 10, 15, 20, 30 and 45	2010/10/21
Amantadine HCl	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Amantadine HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Ambrisentan	Tablet	II (Paddle)	75	0.05 M Acetate Buffer, pH 5.0	900	5, 10, 15, 30, and 45	2009/05/20
Amifampridine	Tablet			Refer to FDA's Dissolution Guidance, 2018			2021/08/19
Amifampridine Phosphate	Tablet			Refer to FDA's Dissolution Guidance, 2018			2021/08/19
Amiloride HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Amiloride HCl/Hydrochlorothiazide	Tablet			Refer to USP			2012/06/07
Aminocaproic Acid	Tablet			Refer to FDA's Dissolution Guidance, 2018			2024/01/03
Aminosalicylic	Granule (Delayed Release)	II (Paddle)	100	Acid Stage: 0.1 N HCl; Buffer Stage 2: pH 7.5 Phosphate Buffer	1000	Acid Stage: 2 hours; Buffer Stage: 1, 2, 3 and 4 hours	2008/07/14
Amiodarone HCl (Test 1)	Tablet			Develop a dissolution method			2023/09/15
Amiodarone HCl (Test 2)	Tablet	I (Basket)	50	Acetate Buffer, pH 4.0, with 1% Tween 80	900	10, 20, 30, 45, 60 and 90	2004/01/12
Amitriptyline HCl	Tablet			Refer to USP			2008/01/14
Amlodipine Besylate	Tablet (Orally Disintegrating)	II (Paddle)	50	0.01 N HCl	500	5, 10, 15 and 20	2008/10/06
Amlodipine Besylate	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Amlodipine Besylate/Atorvastatin Calcium	Tablet	II (Paddle)	75	Phosphate Buffer, pH 6.8	900	5, 10, 15 and 30	2009/04/02